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MicroRNA 146a is recognized for its interaction with intracellular adaptor proteins, including interleukin 1 receptor-associated kinase 1 and tumor necrosis factor receptor-associated factor 6, both of which participate in cytokine-dependent signal transduction and downstream nuclear factor-mediated responses

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This decrease is associated with the cessation of B12 injections at 6 weeks indicating injections may be effective only short-term

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