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For patients requiring an injectable medication, GLP-1 RAs are preferred to insulin due to similar or even better efficacy in A1C reduction, lower risk of hypoglycemia, and reductions in body weight

Benefits include: Average weight loss of up to 15 to 25% in clinical studies Improved portion control and satiety Support for balancing blood sugar and metabolic health GLP-1/GIP Dual Agonists These advanced options activate both GLP-1 and GIP (gastric inhibitory polypeptide) receptors for enhanced appetite control, glucose balance, and fat metabolism

Areflexia can be permanent if neuronal death occurs in the posterior and lateral spinal cord tracts

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