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Do we know if any of them actually had a deficiency

A test is useful to confirm deficiency, but its not always required before starting a private B12 injection course

A Boost To Your Immune System Vitamin B12 is important to your immune system

Not intended for human or veterinary use.) Storage & Handling Store unopened vials at 28C (refrigerated) For long-term storage (6+ months), freeze at 20C or below After reconstitution, keep at 28C and use promptly Protect from light exposure Avoid repeated freeze-thaw cycles Use proper laboratory aseptic technique Technical Data 5-Amino-1MQ is a synthetic quinolinium derivative produced under stringent quality standards

I feel like although the earlier commenters made it out like it's so 'uncommon', it's not at all