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Seemingly, KYNA (and its 7-chloro derivative) can also be effluxed by MRCP4 (ABCC4) as well as by SLC22A6/8 [242,244], as each of these transporters is inhibited by probenecid, whose presence led to an 885-fold increase in the concentration of 7-Cl-KYNA in the prefrontal cortex of rats [242] (see also [240,245,246,247,248,249,250])

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In these situations, the goal is usually to support mobility, maintain tissue stability, and promote consistent recovery during periods of increased physical stress

[DOI] [Google Scholar] 262.Park J., Song W.Y., Ko D., Eom Y., Hansen T.H., Schiller M., Lee T.G., Martinoia E., Lee Y

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