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[1] The cyclic disulfide structure is thought to contribute to conformational rigidity and resistance to peptide degradation in biological environments. Pharmacokinetic studies in murine plasma indicated a plasma half-life of approximately 4 minutes under in vitro conditions, reflecting rapid enzymatic metabolism of the peptide backbone

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The infinitely rapid proliferation of ovarian tumor cells and the high metabolic characteristics of germ cells require large amounts of energy from the mitochondria, which are the main sources of ROS

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NF-B enhances the invasive and adhesive capacities of endometriotic cells to the peritoneal surface by regulating the expression of matrix metalloproteinases, thereby stimulating angiogenesis and inflammation (33)