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The relatively slow pace for developing efficient vaccines is due, at least in part, to the typical complex life cycles of the responsible agents, our limited knowledge of protective immune mechanisms, and the fact that parasites are well adapted to their hosts and evolved complex and efficient mechanisms of immune evasion, including antigenic variation

DIO2 Thr92Ala reduces deiodinase-2 activity and serum-T3 levels in thyroid-deficient patients

Intestinal lymphatic vasculature is functionally adapted to different drainage regions and is altered by helminth infection

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Because vitamin B 12 in supplements is not bound to protein, and because intrinsic factor (IF) is still available, the absorption of supplemental vitamin B 12 is not reduced as it is in pernicious anemia