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PA-treated podocytes showed significantly increased ROS generation, while CD36 inhibition correspondingly reduced ROS levels, suggesting that elevated lipid levels induce CD36-mediated fatty acid uptake and subsequent OS in podocytes, shown as Figure 2a

Metabolite profiling samples were analyzed on applied biosystems, ABSciex 4500 triple quadrupole instrument

High-content imaging of human hepatic spheroids for researching the mechanism of duloxetine-induced hepatotoxicity

The cagrilintide and semaglutide doses were escalated every 4 weeks, with final dose achieved at 16 weeks

In order to prove this hypothesis, we observed the change of sulfur-containing amino acids concentration in blood, synchronized with the changes in GSH after the intravenous administration of GSH