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Since off-label uses are generally not covered by Medicare, Marks B12 shots were not covered, and he had to pay for them out of pocket

The speed at which B12 treats nerve symptoms shows differences between patients

The benefits of vitamin B12 injections include treating or preventing symptoms, such as fatigue, heart problems, neurological damage, mood changes, muscle weakness and hormone imbalances

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Appropriate caution should be exercised while treating severe megaloblastic anemia with cyanocobalamin as intense treatment may lead to hypokalemia and sudden death