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Both the classes share number of conserved residues in the N-terminal GSH binding domain and possess a distinct structural feature of N-terminal extension ( Consequently, these unique properties of GSTs make them important and interesting area of research for the functional characterization

Currently, there are mainly three enzymes that catalyze endogenous H 2 S production, namely, cystathionine gamma-lyase (CSE), 3-mercaptopyruvate sulfurtransferase (3-MST), and cystathionine-beta-synthase (CBS) (Shackelford et al., 2021a)

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