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Normally, protection relies on both exogenous antioxidants (diet, supplements, drugs) and endogenous systems (metabolic pathways) [17,18]

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Zhou Y, Zou J, Xu J, Zhou Y, Cen X, Zhao Y

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Since the low-molecular-weight antioxidants glutathione (GSH) and thioredoxin (Trx-Red or Trx-SH) are cofactors of various enzymes, we may include them in the first line of antioxidant defense (Ighodaro and Akinloye 2018)

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Sufficiency of mesolimbic dopamine neuron stimulation for the progression to addiction

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4 Photo Credit: Freepik Vitamin E works synergistically with glutathione to protect cells from oxidative stress

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