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Anal Cell Pathol (Amst) 2022:2841894 Ghosh S et al (2016) Silymarin protects mouse liver and kidney from thioacetamide induced toxicity by scavenging reactive oxygen species and activating PI3K-Akt pathway
utilized human induced pluripotent stem cells which were derived from cortical spheroids (hCS) to illustrate how PSEN1 mutations affect neurological development, contributing to fAD advancement [43]

Nat Protoc 1(6):3159 Rahman A, Mostofa MG, Nahar K, Hasanuzzaman M, Fujita M (2016) Exogenous calcium alleviates cadmium-induced oxidative stress in rice (Oryza sativa L.) seedlings by regulating the antioxidant defense and glyoxalase systems

reported that curcumin administration significantly improved both cognitive and motor functions in mice compared to disease model controls ( p 84%) without cytotoxic effects

Furthermore, exploring novel delivery systems, such as the proposed cepharanthine-selenium polymer, could enhance bioavailability and therapeutic efficacy
