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Moderately low serum B12 concentrations between 148 or 150 and 221pmol/L or 260pmol/L are often considered indicative of depleted or subclinical B12 deficiency

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These potential applications are supported by small RCTs and mechanistic studies indicating ECM remodeling, antioxidant effects, and anti-inflammation [1, 2, 3, 5, 8]

doi: 10.1038/s41588-021-00880-5 69 BottiniNMusumeciLAlonsoARahmouniSNikaKRostamkhaniMet al