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Phase II/III Comparison of the Platinum Compounds CBDCA vs CHIP vs CACP for Recurrent or Metastatic Epidermoid Carcinoma of the Head and Neck

These compounds do not work through the same pathways

This metabolic route is referred to as the delta5-pathway

What is MOTS-c MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-C) is a 16amino-acid peptide encoded by the mitochondrial genome (mtDNA), making it a rare example of a peptide produced directly by mitochondria rather than nuclear DNA

10.1523/JNEUROSCI.6343-11.2012 68 DuggettN
