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2-Methoxyestradiol ameliorates metabolic syndrome-induced hypertension and catechol- O -methyltransferase inhibited expression and activity in rats
Clinical trials, such as SYDNEY-2 and NATHAN 1, found that taking 600 to 1,200 mg daily improved nerve blood flow and reduced symptoms of neuropathy over several months or years (Ziegler et al., 2006
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