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As additionally demonstrated in (Figure 9), in vivo imaging confirmed the favorable biodistribution of BMI and its strong TME-responsiveness in MRI, highlighting its accumulation and activation within the tumor

PAQR3 regulates endoplasmic reticulum-to-golgi trafficking of COPII vesicle via interaction with Sec13/Sec31 coat proteins

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However, the specific and comprehensive molecular mechanisms, or whether there are associations and crosstalk between these different pathways, remain unclarified

309 Further, a meta-analysis of 13 studies found that although the motor benefits achieved via DBS of the globus pallidus internal (GPi) and STN were similar, DBS of the STN allowed for a greater reduction in medication