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DN30 is involved in decreasing the c-Met signaling pathway through a variety of ways, including c-Met destruction, reducing c-Met expression, c-Met proteolytic detachment, and shedding c-Met from the cell surface, providing traps for HGF [162, 170]
Among these miRNAs, miR-223, the most strongly upregulated miRNA in the mouse model, was further investigated in CRC cell lines
2024 Sep 26;9(1):253
Front Genet 11:49
