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2018;9:e0232517

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(2007) Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2

If target IOP is not achieved in a compliant patient, substitution or addition of newer medications can be considered. Real- world studies have shown both latanoprostene bunod and netarsudil to provide additional IOP reductions in patients already taking three or more medications

Gastroenterology 136 , 14921495 (2009)