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So far two major methods have been used
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doi: 10.1111/jnc.2016.136.issue-3 50 DavisDRAndertonBHBrionJPReynoldsCHHangerDP
[DOI] [PMC free article] [PubMed] [Google Scholar] 162.Del Re DP, Amgalan D, Linkermann A, Liu Q, Kitsis RN
A more recent Danish study in COPD patients with hypertension among 1.3 million people showed that treatment with -blockers reduced COPD hospitalization and mortality more than any other antihypertensive drug 111
