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476 : 5254 Barford D (2004) The role of cysteine residues as redox-sensitive regulatory switches

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While mitochondria have their own antioxidant defenses, including mitochondrial SOD, these defenses are often insufficient to neutralize the high levels of ROS produced during oxidative phosphorylation, especially if mitochondrial function is compromised

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex