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We are conscious of the limitations of the animal models [123], however in a clinical trial undertaken by this group to asses IGF-1 in liver function under cirrhosis with these same dosage (20 g/kg/day) no side effects were reported and liver function greatly increased [108]

When administered by licensed clinicians using medical grade protocols, B1 and B6 injections are generally well tolerated

High doses are generally considered safe, though some people may experience minor side effects

Most at home B12 injection protocols use a standard dose of 1000 mcg (1 mg) per injection

Rapid development of tolerance to the behavioral actions of cholecystokinin