low glutathione chronic fatigue Myalgic encephalomyelitis/chronic syndrome (ME/CFS): diagnosis and management | Journal of Translational Medicine Diseases Linked to LOW GLUTATHIONE

It is a fundamental enzyme cofactor involved in iron oxidation, antioxidant processes, ATP production, norepinephrine synthesis, melanin pigment production, biogenic mono-/diamines oxidation, collagen and elastin cross-linking, blood clotting, immune functions, and activation of selected hormones/peptides

The loss of GSH through the membrane may in turn depend on membrane oxidative stress, because oxidative stress causes lipid peroxidation of cell membrane, leading to altered membrane permeability and transport functions and consequently increased GSH efflux [36]

doi: 10.1053/gast.2001.20875

M.MarcoE.SherrE.LescaG.TillM.et al

Acute effects of insulin-like growth factor I on glucose and amino acid metabolism in the awake fasted rat