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[DOI] [PMC free article] [PubMed] [Google Scholar] 105.Labunskyy V.M., Hatfield D.L., Gladyshev V.N
Occurrence Rates in the United States In the United States, Cyclic Vomiting Syndrome affects many people
J Clin Investig 134(12):e172436
Copper Cofactor for superoxide dismutase (SOD) Copper plays a dual role in oxidative balance: Essential component of copper-zinc superoxide dismutase (CuZnSOD), which neutralizes superoxide radicals Required for ceruloplasmin, which oxidizes ferrous iron (Fe) to less reactive ferric iron (Fe) Necessary for cytochrome c oxidase function in the electron transport chain Supports melanin production, which has antioxidant properties The recommended daily intake of copper is modest (900 g for adults), with both deficiency and excess potentially increasing oxidative stress
Vitamin B12 is a water-soluble vitamin that must be obtained from the diet
