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While RLS affects people of all ages, severe cases of RLS tend to occur in older adults

One significant finding is from the SELECT trial, which showed that long-term use of semaglutide in individuals with obesity but without diabetes led to a 20% reduction in major cardiovascular events and an average weight loss of 9.4%

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Good to know: Emotional well-being after menopause has been linked to improved sleep quality, stabilized cortisol rhythms, and greater parasympathetic resilience effects often supported by lifestyle and, when indicated, low-dose hormone therapy

Primary Handling Editor: Sonia Muliyil, in collaboration with the Nature Medicine team