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Description
Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2

Abstract Obesity is characterized by chronic low-grade inflammation, insulin resistance, impaired skeletal muscle function, and disturbances in neurovascular health
Studies show it increases GH levels without raising stress hormones like cortisol, which can interfere with healing and recovery

therefore, it can be speculated that thyroid hormones and estrogen may have some relationship with depression [116]

Additionally, it plays an important role in the function and regulation of the immune system (77)