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The lack of direct characterization of the glial compartment, the main sources of reactive oxygen species (ROS), limits our conclusions of CBD's effects on the central nervous system (CNS)

A randomized (159), double-blind, placebo-controlled trial involving 46 adult SLE patients (23 in the synbiotic group, 23 in the placebo group) showed that 60 days of synbiotic supplementation significantly increased butyrate metabolism, reduced the pro-inflammatory cytokine IL-6, and inhibited the elevation of hs-CRP

10.1021/jacsau.2c00712

the mutants were, however, processed completely after prolonged incubation

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