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This limitation arises from the multifaceted roles of mitochondrial metabolites in regulating diverse aspects of cellular biology

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Also, hindering pro-inflammatory pathways triggered by Toll-like receptor-LPS (TLR-LPS) and prohibiting Toll-like-receptor-4 (TLR4) activation ( The present study showed that L-carnitine + synbiotic co-supplementation resulted in a significant amelioration in all glycemic parameters including FBS, insulin, HOMA-IR, and QUICKI, compared with L-carnitine + placebo monotherapy, even when adjusted for possible confounding factors

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BMC Pharmacol Toxicol 25 , 32 (2024)