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Int J Oncol 2005(26):369377 Litkouci B, Kwong J, Lo CM, Smedley JG 3rd, McClane BA, Aponte M, Gao Z, Sarno JL, Hinners J, Welch WR, Berkowitz RS, Mok SC, Garner EI (2007) Claudin-4 overexpression in epithelial ovarian cancer is associated with hypomethylation and is a potential target for modulation of tight junction barrier function using C-terminal fragment of Clostridium perfringens enterotoxin