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GrK does not cleave off membrane-bound VEGFR1 from the cell surface, does not release potential sVEGFR1 storage pools from endothelial cells, and does not trigger sVEGFR1 release via protease activating receptor-1 (PAR-1) activation

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These alterations trigger inflammatory cascades through the TLR4/NF-B pathway, while abnormally elevated systemic inflammation indices (NLR, PLR) reflect chronic inflammatory status

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True (d = 1.41) ------------------------------------------------------- VERDICT: REJECT H0