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The Phase 2 clinical trial showed approximately 2-3 kg of additional fat loss compared to placebo over 12 weeks

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In one program, a separate NNMT inhibitor reduced 1-methylnicotinamide levels and improved insulin sensitivity and glucose tolerance in DIO mice, with these effects absent in NNMT-knockout animals

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Studies suggest that lowering NNMT levels may help counteract some of the mechanisms underlying impaired stem cell function in these disorders

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The peptides ability to activate lipolysis while inhibiting lipogenesis creates optimal conditions for fat loss while preserving lean tissue

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