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That requires randomized, controlled, blinded trials with pre-specified endpoints

(Basel) 16 (6), 967 (2021)

Given the role of lactate and lactylation in driving pulmonary vascular remodeling, targeting this metabolic-epigenetic pathway offers a promising therapeutic strategy

Laccase activities were measured using 190 l of reaction mixtures (100 mM citratephosphate buffer pH 4.0 and 1 mM ABTS) in the presence and the absence of a gradient of NaCl (5190 mM) and 10 l of purified LacAnc100 (0.34 g ml 1 ) or LaccID (0.40 g ml 1 ) in flat-bottom 96-well plates (Greiner Bio-One, 655101)