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Study selection and data extraction The titles and abstracts of studies identified by the search strategy were independently screened by two reviewers, and irrelevant studies were excluded

However, in subsequent investigations in rodent models of depression, (2R,6R)-hydroxynorketamine did not exhibit antidepressant-like effects and increased aggressive behavior (Yang et al., 2019)

Allow 2 to 4 weeks of consistent use before expecting noticeable results

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Martinotti, G., Andreoli, S., Reina, D., Di, Nicola M., Ortolani, I., Tedeschi, D., Fanella, F., Pozzi, G., Iannoni, E., D'Iddio, S., and Prof, L
