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Identified in 1973 as a wound-healing modulator, GHK-Cu has since emerged as a key molecule in tissue regeneration, stem-cell activation, anti-inflammatory signaling, and epigenetic gene modulation

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Collagen-related peptide research

[12] It is used in pediatric patients with intrinsic cobalamin metabolic diseases, vitamin B 12 -deficient patients with tobacco amblyopia due to cyanide poisoning, and patients with pernicious anemia who have optic neuropathy

Such deficiencies are caused by several factors, including pernicious anemia, which constitutes a minority of cases, poor dietary intake, or food-bound cobalamin malabsorption (FBCM) (, )