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doi: 10.1073/pnas.1416598111

Purification and characterization of akr1b10 from human liver: role in carbonyl reduction of xenobiotics

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In this paradigm, aquaporin 8 silencing, which is specifically expressed in IMM, enhances mitochondrial ROS generation and results in mitochondrial depolarization and cell death (Marchissio et al., 2012)