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Research suggests that 25% to 30% of weight lost on GLP-1 agonists can be lean mass rather than fat, particularly when protein intake is inadequate
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Journal (Pharmaceuticals, Sep 28, 2025, 18(10), 1450)
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224 The lysine deacylase activity of SIRT4 is involved in the control of leucine metabolism and insulin secretion through regulating the acylation status of enzymes in these pathways
