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Also, it should be noted that the release of interleukin (IL)-6, a central mediator of inflammation, can be induced by ROS [176, 177]

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Following Lonza's acquisition of capsugel last year, the company have positioned themselves as being able to combine active ingredients along with delivery systems and finished dosage forms, which in turn brings a unique offering to the market, Beth Tormey, Head of Global Business Unit at Lonza tells NutritionInsight at this years Vitafoods Europe

5.2.2 Ameliorating inflammation and oxidative stress Dihydroartemisinin reduces the expression of TGF-1, a key factor in fibrosis, and inhibits the activation of JAK2 and STAT3, thereby decreasing the expression of the inflammatory factors, such as IL-1, IL-6, TNF-, and chemokine ligand 3, and reducing the infiltration of inflammatory cells (You et al., 2022)