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PMID: 34827486 Dihexa purchased from MedChemExpress

This therapeutic effect was supported by a particular gene expression in the hippocampal tissues that appeared in BPC 157-treated rats [48]

Mechanistic research focuses on nitric oxide signaling, vascular homeostasis, cellular-membrane stability, and tissue responses to chemically induced injury

The literature was monitored as the manuscript was developed, and papers identified reviewed for relevance

Whilst the true (not anecdotal or case reports) effects on melasma are lacking via large studies there are some reports that it can help with melasma pigmentation, especially in combination with procedures such as lasers & novel chemical peels