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Accessed May 21, 2018

[DOI] [PMC free article] [PubMed] [Google Scholar] 130.Laposata EA, Lange LG

doi: 10.1016/j.soilbio.2004.10.021 76 FilekM.LabanowskaM.KocielniakJ.Biesaga-KocielniakJ.KurdzielM.SzarejkoI.et al

Riboflavin is critical to the proper functioning of mitochondrial pathways, and mitochondrial dysfunction linked to riboflavin deficiency is linked to many neurological conditions, including AD, PD, MS, Alper's syndrome, and Kearns Sayre Syndrome, reviewed in Ref

Thus, an indirect strategy to target c-Myc translation is to pharmacologically inhibit the mTOR kinase or one of the mTORC1 effector proteins
