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Che M., Wei W., Yang X., et al., RadiationInduced Upregulation of Itaconate in Macrophages Promotes the Radioresistance of NonSmall Cell Lung Cancer by Stabilizing NRF2 Protein and Suppressing Immune Response, Redox Biology 85 (2025): 103711

reported a significant correlation between vanin-1 gene expression and HbA1c level 9

Primary research: Neuroprotection, cellular survival, age-related cognitive decline Mechanism: Activates STAT3 signaling, inhibits Bax-mediated apoptosis, and interacts with IGFBP-3 Regulatory status: Not FDA-approved

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Muthayya S, Kurpad AV, Duggan CP, et al