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However, the banned status in sports does not affect its availability for legitimate research

Tingling in extremities, brain fog, or mood changes alongside training struggles particularly point toward possible deficiency

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This difference may be explained by the results of in vitro binding studies, which showed that daratumumab can directly bind CD38 on RBCs, whereas isatuximab requires a cofactor (e.g., a mouse anti-CD38 antibody or a CD38 inhibitor), suggesting masking of the isatuximab epitope on RBCs in some patients [49, 50]