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Although pioglitazone is recommended for patients with biopsy-proven NASH, the efficacy and safety of the drug in the long-term demands more studies ( Reference Chalasani, Younossi and Lavine 72 )

(2020) Polyethylene glycol-fusion repair of sciatic allografts in female rats achieves immunotolerance via attenuated innate and adaptive responses

THP-1 monocyte culture and induced differentiation THP-1 cell lines were maintained in RPMI-1640 (HyClone, USA), 10% FBS, and 100 units/mL penicillin and 100 g/mL streptomycin (HyClone, USA) at 37 C under a humidified atmosphere of 5% CO 2

Conversely, previously published studies with genetic FAK FAT domain inhibitor, Ad-FRNK, reported selective inhibition of cancer cell viability and limited effects on normal cell viability 19,39