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It is an intracellular metabolic-enzyme modulator, which is why its research read-outs are things like NAD+ levels and adipocyte gene expression, not how full you feel. That mechanistic distinction is the single most important thing to understand before looking at any dose number

doi: 10.20452/pamw.16222 8 Dhillon-SmithRKCoomarasamyA

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Quality control systems in cardiac aging

doi: 10.1073/pnas.0503624102
