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Low levels or loss of the EZH2 protein are associated with chemoresistance and a poor prognosis (175)
[DOI] [PubMed] [Google Scholar] 45.Tsikas D., Sawa M., Brunner G., Gutzki F., Meyer H., Frolich J
doi: 10.1016/j.freeradbiomed.2023.09.006 33 ZhouXZhouRRaoXHongJLiQJieXet al
PMID: 32389639
Furthermore, emodin nanocapsules targeting macrophage mannose receptors regulate lipid metabolic reprogramming to influence polarization (285), while biomimetic nanoparticles delivering SIRT1 inhibitors suppress M2 polarization via the PI3KAkt/NF-B pathway, preventing hepatitis B-related hepatocellular carcinoma (286)
