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Single-receptor, dual-receptor, and triple-receptor agonists represent an escalating spectrum of metabolic intervention, and the dosing complexity increases proportionally with each additional receptor target
Panatta E, Zampieri C, Melino G, Amelio I

Repeated METH misuse leads to loss of control over drug use, compulsive use despite negative consequences, and multiple relapse episodes in humans who meet diagnostic criteria for METH use disorder (MUD) (DSM-5, 2013)

JAMM, JAB1/MPN+/MOV34
