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In general, class I ferroptosis inducers that are typically used are erastin (113) (which inhibits Xc cystine uptake), glutamate (121) (which inhibits glutamate transfer to reduce Xc activity) and sulfasalazine (122) (which inhibits Xc in the cell membrane)

And much more attentions have been drawn to the TCM active ingredients showing a definite effect and a clear structure

[DOI] [Google Scholar] 147.Larese Filon F., Mauro M., Adami G., Bovenzi M., Crosera M
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Integrin v1 interacts with stromal cell adhesion molecules to convey such signals [80]
