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Semax is a synthetic peptide derived from a fragment of adrenocorticotropic hormone, specifically the sequence ACTH(4-7), with additional amino acids added to improve its stability and bioavailability

Nature 411 , 599603 (2001)

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Retinal microglia, the resident yolk sac-derived macrophage cells in the retina, act as the first and key active immune defense in the central nervous system, constantly scavenging for plaques, damaged or unnecessary neurons and synapses, and infectious agents [88]

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