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120 ROS play crucial modulatory roles in amplifying distal TCR pathways, including Ca 2+ -calcineurin-NFAT, IKK-NF-B, Ras-ERK1/2, and mTOR cascades, which in turn enhance T-cell activation, proliferation, and cytokine production (e.g., IL-2)

Gene 2000, 254 (1), 237243

Z., Lieberman, M

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