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Oral Dosing Runs Higher Injectable: 200 to 500mcg per dose Oral: 500 to 1,000mcg per dose, once or twice daily, taken on an empty stomach Higher oral doses are used to make up for the fact that the gut absorbs the compound poorly compared to injections

However, if this occurred with chronic acetaminophen ingestion, why would the -glutamyl cysteine enter the dotted line pathway, be catalyzed by -glutamylcyclotransferase, and release cysteine and 5-oxoproline

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Some researchers prefer longer cycles (6-8 weeks) with equal time off