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To further identify pathways that were potentially pathogenic in UC, and targeted or reversed by VDZ, we then filtered for DE genes that were up-regulated in UC vs HC, and reciprocally down-regulated in UC-VDZ vs UC, and vice versa (Fig
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However, no significant effects were observed on IOP, visual acuity, central corneal thickness (CCT), ganglion cell complex (GCC) on optical coherence tomography (OCT), or quality of life measures (NCT04088084)

Gene regulation by long non-coding RNAs and its biological functions
Jana S, Sinha M, Chanda D, Roy T, Banerjee K, Munshi S, et al
