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PMID: 7994442 Howell L (2024): FDA approves neffy for allergic reactions

6b) While this would impair killing of VSMC and VEC, which could help prevent ASCVD progression, it would similarly prevent CD8 + T cells from suppressing inflammatory CD4 + T cells, APCs that promote immune activation, and plasma cells that produce inflammatory IgG 2,4

The exact cause for this phenomenon cannot be ascertained as of now

Plant Cell 22(2):376391

While there is significant debate on whether this sustained immune response is the primary mechanism responsible for long-COVID or a byproduct of other underlying mechanisms (Altmann et al., 2023), a common theme among these disorders appears to be sustained inflammatory cascades that persist beyond the resolution of the initial insult (Clark, 2022)