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However, a landmark July 2025 study published in the Proceedings of the National Academy of Sciences (PNAS) by Shankar, Davis, Bonilla, et al., revealed a fascinating and complex paradox regarding redox homeostasis in these conditions

Skibsted and colleagues demonstrated that AX radical cation is effectively reduced by polyphenols such as isoflavonoids, in addition to the antioxidants mentioned earlier [168]

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To reinforce the translational relevance of these findings, additional in vivo evidence is essential